Ultrasound-Derived Fat Fraction (UDFF) for Monitoring Liver Steatosis in MASLD: A Case Report

A Case Report | Open Access

Volume 2025 - 4 | Article ID 273 | http://dx.doi.org/10.51521/WJCRCI.2025.e42.417

Ultrasound-Derived Fat Fraction (UDFF) for Monitoring Liver Steatosis in MASLD: A Case Report

Academic Editor: John Bose

Received 2025-09-19
Revised 2025-10-10
Accepted 2025-10-13
Published 2025-10-15

Lifecore Clinic LLC, AbuDhabi, United Arab Emirates

*Corresponding author: Kiran Mukhtar, Sonographer Clinical Imaging, Life Core Private Clinic LLC, Royal Group Headquarters (7th Floor), Al Salam Street, PO Box 63811, Abu Dhabi, United Arab Emirates.

Citation: Kiran Mukhtar, Shafaath Husain Syed Mohammed, Muhammad Raza Qureshi, Faiz Ul Amin (2025) Ultrasound-Derived Fat Fraction (UDFF) for Monitoring Liver Steatosis in MASLD: A Case Report. World J Case Rep Clin Imag. 2025 October; 4(2)1-5.

Copyrights: © Kiran Mukhtar, et al., 2025, This article is licensed under the Creative Commons Attribution-Non Commercial-4.0-International-License-(CCBY-NC) (https://worldjournalofcasereports.org/blogpage/copyright-policy). Usage and distribution for commercial purposes require written permission.

Abstract

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is prevalent among individuals with metabolic risk factors. Accurate, non-invasive quantification of hepatic steatosis is crucial for diagnosis and management.

Case Presentation: We report a 52-year-old male (BMI 30.6 kg/m²) with prediabetes and mild dyslipidemia, who underwent lifestyle modification including dietary changes and increased physical activity. Baseline hepatic fat content was assessed using UDFF on the Siemens ACUSON Sequoia system, yielding a mean UDFF of 17%, consistent with moderate hepatic steatosis. After a 6-month intervention period, the patient achieved a BMI reduction to 26.5 kg/m². Follow-up UDFF showed a mean value of 5%, indicating resolution of steatosis.

Results: Quantitative analysis demonstrated a substantial reduction in liver fat fraction (from 17% to 5%) accompanied by an improvement in body composition.

Conclusion: UDFF effectively monitored changes in hepatic steatosis corresponding with lifestyle-induced weight loss. Its non-invasive nature and accessibility make it a valuable tool for managing MASLD in clinical settings.