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World Journal of Case Reports and Clinical Images
World Journal of Case Reports and Clinical Images
Research Article | Open Access
Volume 2025 - 4 | Article ID 267 | http://dx.doi.org/10.51521/WJCRCI.2025.e41.412
Academic Editor: John Bose
Hernandez Lozada Victor Hugo, Buendia
Santiago Luis Ricardo, Julio Cesar Meza Sanchez, Ledesma Santos Juan Martin
Corresponding Author: Atte Luis Ricardo Buendia Santiago, General Surgeon.
Citation: Hernandez Lozada Victor Hugo, Buendia Santiago Luis Ricardo, Julio
Cesar Meza Sanchez, Ledesma Santos Juan Martin (2025) Severity Correlation
Between Helicobacter pylori Infection and Gastritis: A Cross-Sectional,
Sex-Stratified Study in a Primary Care Hospital, in Mexico City. World J Case
Rep Clin Imag. 2025 June; 4(1)1-3.
Copyrights: Atte Luis Ricardo Buendia Santiago, et al., 2025, This article is
licensed under the Creative Commons Attribution-Non
Commercial-4.0-International-License-(CCBY-NC)
(https://worldjournalofcasereports.org/blogpage/copyright-policy). Usage and
distribution for commercial purposes require written permission.
Abstract
Background: Helicobacter pylori (H.
pylori) is a major cause of chronic gastritis and is associated with the
progression of gastric pathology. The present study aimed to examine the
relationship between gastritis severity and the presence of H. pylori,
considering sex-based differences, in a clinical population from Mexico City.
Methods: A cross-sectional study was conducted on 348 patients (139 men and 209
women) who underwent endoscopy in a hospital in Mexico City. Gastritis severity
was categorized into four levels (1 = mild, 2 = moderate, 3 = severe, 4 =
diffuse). The presence of H. pylori was confirmed through
standard diagnostic tests. Pearson correlation coefficients were calculated to
assess the association between gastritis severity and H. pylori infection
separately by sex. Chi-square tests were used to evaluate associations between
categorical variables. Results: Among all patients, 219 (62.9%) tested positive
for H. pylori. A statistically significant correlation was found between
gastritis severity and H. pylori positivity in both sexes: women (r = 0.395, p
< 0.001) and men (r = 0.177, p = 0.029). The chi-square test showed no significant
association between sex and H. pylori infection (Chi2 = 1.30,
p = 0.255). Conclusion: There is a positive correlation between the severity of
gastritis and the presence of H. pylori, particularly among women.
These findings suggest that H. pylori infection may play a
more pronounced role in the pathogenesis of severe gastritis in female
patients.
Keywords: H. pylori, Gastritis, Cross-Sectional Study, Mexico City,
Correlation, Sex Differences
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