Case Report | Open Access
Volume 2023 - 2 | Article ID 220 | http://dx.doi.org/10.51521/WJCRCI.2023.2201
Academic Editor: Guangyu Li
Fares A Alkhayal1, Ali A
Alkinani2
1Dermatology and dermatologic surgery department, Prince Sultan Military
Medical City, Email: falkhayal@outlook.com
2Medical Service Directorate of Joint Force Command,
Corresponding Author: Fares A Alkhayal, Dermatology and dermatologic surgery department,
Prince Sultan Military Medical City, Email: falkhayal@outlook.com
Citation: Fares A Alkhayal, Ali A Alkinani (2023) Diffuse Face and Ear
Hypertrichosis Caused by 5% Topical minoxidil in an Adult Woman with
spontaneous resolution & (Review of literature). World J Case Rep Clin
Imag. 2023 April-June; 2(2)1-3.
Copyrights © 2023, This article is licensed under the Creative Commons
Attribution-Non Commercial-4.0-International-License-(CCBY-NC)
(https://worldjournalofcasereports.org/blogpage/copyright-policy). Usage and
distribution for commercial purposes require written permission.
Background:
Minoxidil is a vasodilator medication
known for its ability to promote hair growth. Although it was first introduced
as an oral drug to treat hypertension, minoxidil was observed to have the
important side-effect of increasing hair growth; this led to the development of
a topical formulation as a 2% concentration solution for the treatment of
female androgenic alopecia (AGA) and 5% for treating male AGA, which is
considered nowadays as a first line US Food and Drug Administration
(FDA)-approved treatment for AGA in addition to oral 5-alpha-reductase
inhibitor (finasteride) [1]. The mechanism by which minoxidil promotes hair
growth is not fully understood but can be related to increasing blood flow due
to its vasodilator effects [2]. AGA is characterized by the gradual conversion
of terminal hairs into vellus hairs. Alterations in the hair cycle include
reduced duration of the anagen phase and increased duration of the telogen
phase, resulting in shorter hairs and eventual balding [3]. Side-effects of
topical minoxidil include an irritant and allergic contact dermatitis, pruritus,
and facial hypertrichosis, which are more often seen with use of 5% solutions
rather than 2% [3]. Herein we report the case of a 24-year-old female who
developed severe ear and face hypertrichosis after using topical 5% solution
minoxidil and who later received spontaneous resolution of her hypertrichosis.
Keyword: Hypertrichosis, Minoxidil
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